Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Sep-Dec;7(3):118-20.
doi: 10.5005/jp-journals-10008-1148. Epub 2013 Sep 6.

Pseudoexfoliation Syndrome

Murali Ariga  1 , M Nivean  2 , P Utkarsha  3
Affiliations
Review

Pseudoexfoliation Syndrome

Murali Ariga et al. J Curr Glaucoma Pract. 2013 Sep-Dec.

Abstract

Pseudoexfoliation (PXF) syndrome is a well-recognized clinical entity of considerable clinical significance. It is associated with poor mydriasis, cataracts with weak zonular support, secondary glaucoma and possibly with biochemical abnormalities, such as elevated homocysteine and systemic diseases involving the cardiovascular and central nervous system. There have also been some recent studies identifying mutations in genes which are associated with PXF. How to cite this article: Ariga M, Nivean M, Utkarsha P. Pseudoexfoliation Syndrome. J Current Glau Prac 2013;7(3): 118-120.

Keywords: Homocysteine; Mutations.; Mydriasis; Pseudoexfoliation; Secondary glaucoma; Weak zonules.

PubMed Disclaimer

Conflict of interest statement

Source of support: Nil

Conflict of interest: None declared

Figures

Fig. 1
Fig. 1
Goniophotograph showing increased TM pigmentation in PXF
Fig. 2
Fig. 2
PXF material in angle
Fig. 3
Fig. 3
Classic pattern of PXF seen in the lens
Fig. 4
Fig. 4
Fibrillar PXF material seen in pupillary border
Fig. 5
Fig. 5
PXF material on corneal endothelium
See this image and copyright information in PMC

References

    1. Vessani RM, Ritch R, Liebmann JM, Jofe M. Plasma homocysteine is elevated in patients with exfoliation syndrome. Am J Ophthalmol. 2003 Jul;136(1):41–46. - PubMed
    1. Prince AM, Ritch R. Clinical signs of the pseudoexfoliation syndrome. Ophthalmology. 1986 Jun;93(6):803–807. - PubMed
    1. Puska P, Vasara K, Harju M, Setälä K. Corneal thickness and corneal endothelium in normotensive subjects with unilateral exfoliation syndrome. Graefes Arch Clin Exp Ophthalmol. 2000 Aug;238(8):659–663. - PubMed
    1. Naumann GO, Schlötzer-Schrehardt U. Keratopathy in pseudoexfoliation syndrome as a cause of corneal endothelial decompensation: a clinicopathologic study. Ophthalmology. 2000 Jun;107(6):1111–1124. - PubMed
    1. Pohjanpelto P. Long-term prognosis of visual field in glaucoma simplex and glaucoma capsular. Acta Ophthalmol (Copenh) 1985 Aug;63(4):418–423. - PubMed

LinkOut - more resources