Primary pulmonary leiomyosarcoma: A case report

Abstract

Primary pulmonary leiomyosarcoma (PPL) is an extremely rare malignant tumor. It has been revealed that PPL may originate from the smooth muscle of the pulmonary parenchyma, pulmonary arteries and bronchi. Patients with PPL may be asymptomatic or present with symptoms similar to those observed in other primary lung tumors. The present study reports the case of a 48-year-old man who presented with a lung mass and underwent a right upper-middle lobe bronchoscope tumor resection. The patient was subsequently diagnosed with PPL. Following the bronchoscopic tumor resection, chemotherapy was administered to the patient; however, the patient succumbed to the disease after the second cycle of chemotherapy.

Keywords: chemotherapy; primary pulmonary leiomyosarcoma.

Figure 1.

Enhanced computed tomography scans of the chest revealing the presence of a large irregular mass extending into the right pulmonary bronchi, with circumferential narrowing of the upper lobe and anterior segmental bronchus.

Figure 2.

(A) Bronchial 3-dimensional reconstruction. (B) Computed tomography coronal plane of the chest.

Figure 3.

Bronchoscopy images (A) prior to surgery, revealing visible neoplasms in the respiratory tract lumen (black arrow), which caused the lumen to become decreased in diameter, and (B) following successful resection with a flexible bronchoscope.

Figure 4.

Hematoxylin and eosin staining of the resected primary pulmonary leiomyosarcoma, composed of spindle cells arranged in interweaving bundles. Magnification, ×200.