Hepatocyte Growth Factor and Satellite Cell Activation

Abstract

Satellite cells are the "currency" for the muscle growth that is critical to meat production in many species, as well as to phenotypic distinctions in development at the level of species or taxa, and for human muscle growth, function and regeneration. Careful research on the activation and behaviour of satellite cells, the stem cells in skeletal muscle, including cross-species comparisons, has potential to reveal the mechanisms underlying pathological conditions in animals and humans, and to anticipate implications of development, evolution and environmental change on muscle function and animal performance.

Keywords: Cytoskeleton; DGC; Growth; HGF; Muscle atrophy; Nitric oxide; Regeneration; Skeletal muscle; Zebrafish; c-met receptor.