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. 2017 Feb 1;46(1):24.
doi: 10.1093/ije/dyw006.

Cohort Profile: The Health Outcomes and Measures of the Environment (HOME) study

Joseph M Braun  1 , Geetika Kalloo  1 , Aimin Chen  2 , Kim N Dietrich  2 , Stacey Liddy-Hicks  3 , Samantha Morgan  3 , Yingying Xu  3 , Kimberly Yolton  3 , Bruce P Lanphear  4   5
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Cohort Profile: The Health Outcomes and Measures of the Environment (HOME) study

Joseph M Braun et al. Int J Epidemiol. .
No abstract available

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Figures

Figure 1
Figure 1
Eligibility and enrolment flowchart for the HOME Study.
Figure 2
Figure 2
Confounder- and exposure-adjusted associations between maternal gestational urinary or serum endocrine disrupting chemical concentrations and Social Responsiveness Scale (SRS) total t-scores in 4- and 5-year-old Cincinnati children. PCB-66, PCB-101, PCB-157, PCB-167, PCB-172, PCB-177, PCB-178, PCB-195, PCB-209, β-HCH, DDT, PBDE-85, PBDE-154,and PBDE 183 are coded as detected vs non-detectable. The displayed betas are the change in SRS scores among children born to women with detectable vs non-detectable levels of these chemicals. All other chemicals were treated as continuous log10-transformed variables that are divided by two times their standard deviation to put them on a comparable scale to the dichotomous variables. Adjusted models include maternal age, race, marital status, education, parity, insurance status during pregnancy, prenatal vitamin use, employment during pregnancy, IQ, household income, depressive symptoms during pregnancy, caregiving environment score, gestational serum cotinine concentration and all chemical biomarker concentrations. Horizontal lines indicate the 95% confidence interval around the point estimate.
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