Practical Value of Food Pathogen Traceability through Building a Whole-Genome Sequencing Network and Database
- PMID: 27008877
- PMCID: PMC4963501
- DOI: 10.1128/JCM.00081-16
Practical Value of Food Pathogen Traceability through Building a Whole-Genome Sequencing Network and Database
Abstract
The FDA has created a United States-based open-source whole-genome sequencing network of state, federal, international, and commercial partners. The GenomeTrakr network represents a first-of-its-kind distributed genomic food shield for characterizing and tracing foodborne outbreak pathogens back to their sources. The GenomeTrakr network is leading investigations of outbreaks of foodborne illnesses and compliance actions with more accurate and rapid recalls of contaminated foods as well as more effective monitoring of preventive controls for food manufacturing environments. An expanded network would serve to provide an international rapid surveillance system for pathogen traceback, which is critical to support an effective public health response to bacterial outbreaks.
Copyright © 2016, American Society for Microbiology. All Rights Reserved.
Figures
References
-
- Hoffmann M, Luo Y, Monday SR, Gonzales-Escalona N, Ottensen A, Muruvanda T, Wang C, Kastanis G, Keys C, Janies D, Senturk I, Catalyurek UV, Wang H, Hammack TS, Wolfgang WJ, Schoonmaker-Bopp D, Chu A, Myers R, Haendiges J, Evans P, Meng J, Strain E, Allard MW, Brown EW. 2016. Tracing origins of the Salmonella Bareilly strain causing a food-borne outbreak in the United States. J Infect Dis 213:502–508. doi:10.1093/infdis/jiv297. - DOI - PubMed
-
- Hoffmann M, Zhao S, Pettengill J, Luo Y, Monday SR, Abbott J, Ayers SL, Cinar HN, Muruvanda T, Li C, Allard M, Whichard J, Meng J, Brown EW, McDermott PF. 2014. Comparative genomic analysis and virulence differences in closely related Salmonella enterica serotype Heidelberg isolates from humans, retail meats, and animals. Genome Biol Evol 6:1046–1068. doi:10.1093/gbe/evu079. - DOI - PMC - PubMed
-
- Chen Y, Mukherjee S, Hoffmann M, Kotewicz M, Young S, Abbott J, Luo Y, Davidson M, Allard MW, McDermott PF, Zhao S. 2013. Whole-genome sequencing of gentamicin-resistant Campylobacter coli isolated from U.S. retail meats reveals novel plasmid mediated aminoglycoside resistance genes. Antimicrob Agents Chemother 57:5398–5405. doi:10.1128/AAC.00669-13. - DOI - PMC - PubMed
-
- Gordon NC, Price JR, Cole K, Everitt R, Morgan M, Finney J, Kearns AM, Pichon B, Young B, Wilson DJ, Llewelyn MJ, Paul J, Peto TE, Crook DW, Walker AS, Golubchik T. 2014. Prediction of Staphylococcus aureus antimicrobial resistance by whole-genome sequencing. J Clin Microbiol 52:1182–1191. doi:10.1128/JCM.03117-13. - DOI - PMC - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical