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. 2015 Dec;77(Suppl 3):1209-13.
doi: 10.1007/s12262-015-1251-6. Epub 2015 Mar 8.

A Comparative Study of Honey and Phenytoin Dressings for Chronic Wounds

Siddharth P Dubhashi  1 , Rajat D Sindwani  1
Affiliations

A Comparative Study of Honey and Phenytoin Dressings for Chronic Wounds

Siddharth P Dubhashi et al. Indian J Surg. 2015 Dec.

Abstract

Chronic wounds are a common problem faced by health care professionals, both in the community and in the hospital setting. The aim of this study was to evaluate the use of honey and phenytoin with respect to the process of wound healing, eradication of infection, pain relief and hospital stay. The study included 150 patients, 3 groups of 50 each (group A, honey dressing; group B, phenytoin dressing; group C, saline dressing). The appearance of granulation tissue was faster with significant wound area reduction after 3 weeks in groups A and B compared to group C. Eradication of infection was evident earlier in the honey- and phenytoin-treated groups along with significant pain relief as compared to that of group C. The outcomes of the use of honey and phenytoin as wound dressings are beneficial and comparable. Honey provides quicker pain relief and removes malodour more effectively.

Keywords: Chronic wound; Honey; Infection; Pain relief; Phenytoin.

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Figures

Fig. 1
Fig. 1
Graph showing time of appearance of granulation tissue in the three groups
Fig. 2
Fig. 2
Wound healing with honey and phenytoin dressings. a Honey dressing. b Phenytoin dressing
See this image and copyright information in PMC

References

    1. Hasamnis AA, Mohanty BK, Muralikrishna, Patil S. Evaluation of wound healing effect of topical phenytoin on excisional wound in albino rats. J Young Pharm. 2010;2:59–62. doi: 10.4103/0975-1483.62215. - DOI - PMC - PubMed
    1. Werdin F, Tenenhaus M, Rennekampff HO. Chronic wound care. Lancet. 2008;372:1860–1862. doi: 10.1016/S0140-6736(08)61793-6. - DOI - PubMed
    1. Sharma RK, John JR. Role of stem cells in the management of chronic wounds. Indian J Plast Surg. 2012;45:237–243. doi: 10.4103/0970-0358.101286. - DOI - PMC - PubMed
    1. Archer HG, Barnett S, Irving S, Middleton KR, Seal DV. A controlled model of moist wound healing; comparison between semipermeable film, antiseptics and sugar paste. J Exp Pathol. 1990;71:155–170. - PMC - PubMed
    1. Lawrence JC. Honey and wound bacteria: editorial. J Wound Care. 1999;8(4):155. doi: 10.12968/jowc.1999.8.4.26172. - DOI - PubMed

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