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Review
. 2015 Dec;77(Suppl 3):1313-7.
doi: 10.1007/s12262-014-1099-1. Epub 2014 May 16.

Neutrophil Gelatinase Associated Lipocalin (NGAL) as a Biomarker. Does It Apply in Abdominal Aortic Aneurysms? A Review of Literature

Georgios Karaolanis  1 , Demetrios Moris  2 , Viktoria-Varvara Palla  1 , Euridiki Karanikola  1 , Chris Bakoyiannis  2 , Sotirios Georgopoulos  2
Affiliations
Review

Neutrophil Gelatinase Associated Lipocalin (NGAL) as a Biomarker. Does It Apply in Abdominal Aortic Aneurysms? A Review of Literature

Georgios Karaolanis et al. Indian J Surg. 2015 Dec.

Abstract

Neutrophil gelatinase associated lipocalin (NGAL) as a protein derived from neutrophils has recently been the field of investigation in a wide range of diseases (renal disease, coronary artery disease, etc). The MEDLINE/PubMed database was searched for publications with the medical subject heading "NGAL" and keywords "Abdominal aortic aneurysm (AAA)," "biomarker," and "growth". We restricted our search to date. In this review, we included 38 articles and abstracts that were accessible and available in English. An effort to further explain the role of NGAL within AAA has been made. NGAL seems to be a hopeful marker for the pathogenesis and the progression of abdominal aortic aneurysms (AAAs), which has significant morbidity and mortality rates.

Keywords: Abdominal aortic aneurysm (AAA); Biomarkers; Growth; Neutrophil gelatinase associated lipocalin (NGAL).

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