Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Jan-Mar;19(1):9-20.
doi: 10.4103/0972-2327.167713.

Research in Parkinson's disease in India: A review

Pratibha Surathi  1 , Ketan Jhunjhunwala  1 , Ravi Yadav  1 , Pramod Kumar Pal  1
Affiliations
Review

Research in Parkinson's disease in India: A review

Pratibha Surathi et al. Ann Indian Acad Neurol. 2016 Jan-Mar.

Abstract

Parkinson's disease (PD) is a common neurodegenerative disorder affecting patients in large numbers throughout the world. In this article, we review all the published data on PD based on studies in Indian population. We have tried to consolidate the contribution of Indian studies in PD research. We found 95 articles, of which 92 were original research papers. This is a relatively less number, but in the last decade, there has been an increase in research on PD from this country. But most of them seem to be restricted to only a few research institutes. The nonmotor symptoms and genetics are the most commonly studied aspects. The systematic review of the articles reveals that the epidemiology in India may be different with relatively lesser incidence here. Most of the genetic mutations found to cause PD in other population are not found in India, revealing that other genetic factors may be involved. Further research needs to be encouraged to understand the disease in Indian patients better, as all the results cannot be extrapolated from the Western literature to this heterogeneous Indian population. There need to be more studies on therapeutic aspects of the disease.

Keywords: Epidemiology; India; Parkinson's disease; genetics; treatment.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: None declared.

Figures

Figure 1
Figure 1
Number of publications on Parkinson's disease from India; year wise
Figure 2
Figure 2
Number of publications on Parkinson's disease from India from various institutions. A = National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, B = All India Institute of Medical Sciences (AIIMS), New Delhi, C = Bangur Institute of Neurosciences/ Anthropology Society of India, Kolkata, D = NIMHANS+ AIIMS, E = Sree Chitra Tirunal Institute of Medical Sciences and Technology (SCT), Trivandrum, F = Madras Medical College (MMC), Chennai, G = Bombay Hospital, Mumbai, H = Neurospeciality Centre, Belgaum, I = Sher-e-Kashmir, Srinagar, J = Post Graduate Institute, Chandigarh, K = Parkinson's Disease Foundation, Bangalore + AIIMS
See this image and copyright information in PMC

References

    1. Pearce JM. Aspects of the history of Parkinson's disease. J Neurol Neurosurg Psychiatry. 1989;Suppl:6–10. - PMC - PubMed
    1. Singhal B, Lalkaka J, Sankhla C. Epidemiology and treatment of Parkinson's disease in India. Parkinsonism Relat Disord. 2003;9(Suppl 2):S105–9. - PubMed
    1. de Lau LM, Breteler MM. Epidemiology of Parkinson's disease. Lancet Neurol. 2006;5:525–35. - PubMed
    1. Gourie-Devi M, Gururaj G, Satishchandra P, Subbakrishna DK. Prevalence of neurological disorders in Bangalore, India: A community-based study with a comparison between urban and rural areas. Neuroepidemiology. 2004;23:261–8. - PubMed
    1. Das SK, Biswas A, Roy T, Banerjee TK, Mukherjee CS, Raut DK, et al. A random sample survey for prevalence of major neurological disorders in Kolkata. Indian J Med Res. 2006;124:163–72. - PubMed