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Case Reports
. 2016 Jan-Apr;9(1):75-8.
doi: 10.4103/0974-2069.171398.

Co-occurrence of Takayasu's arteritis and tuberculosis: Report of a Tunisian pediatric case

Monia Khemiri  1 , Wiem Douira  2 , Sihem Barsaoui  1
Affiliations
Case Reports

Co-occurrence of Takayasu's arteritis and tuberculosis: Report of a Tunisian pediatric case

Monia Khemiri et al. Ann Pediatr Cardiol. 2016 Jan-Apr.

Abstract

Few reports on co-occurrence of Takayasu's arteritis (TA) and tuberculosis (Tb) have been published in childhood. A 12-year-old girl presented with 4-month's history of a dry cough, persistent fever, marked weakness, and weight loss. Physical examination revealed impalpable peripheral pulses and unrecordable blood pressure (BP) on upper limbs. In lower limbs, peripheral pulses were normal and BP reached respectively 160/90 and 140/87 mmHg. Laboratory investigations showed an erythrocyte sedimentation rate at 140 mm in the 1(st) h and microcytic anemia (8.6 g/dl). Doppler ultrasound and computed tomography angiography revealed significant thickening of the aortic-arch and both common carotid arteries wall, with luminal narrowing of the right common carotid and its branches and severe stenosis of the left subclavian artery. Simultaneously, the diagnosis of active pulmonary Tb was achieved based on radiological data, positive Mantoux test and successful response to antitubercular drugs. During follow-up, corticostetroids and methotrexate were required to control TA relapses.

Keywords: Child; takayasu arteritis; tuberculosis.

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Figures

Figure 1
Figure 1
(a) Cervical computed tomography angiography scans (sagittal section) circumferential wall thickening of both common carotid arteries, (b) cervical computed tomography angiography scans (cross section) stenosis of the 2/3 vascular area of the right common carotid
Figure 2
Figure 2
(a) Cervical computed tomography angiography scans (cross section), (b) cervical computed tomography angiography scans (sagittal section) a left subclavian artery, severe stenosis of two centimeters
Figure 3
Figure 3
(a) Thoracic computed tomography angiography scans, bilateral pulmonary nodes, (b) thoracic computed tomography angiography scans (mediastinal window), hilary lymphadenopathy
See this image and copyright information in PMC

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