MITF Drives a Reversible Drug-Tolerant State in Melanoma
- PMID: 27012829
- DOI: 10.1158/2159-8290.CD-RW2016-053
MITF Drives a Reversible Drug-Tolerant State in Melanoma
Abstract
PAX3-mediated upregulation of MITF promotes mutation-independent tolerance to MAPK inhibition.
©2016 American Association for Cancer Research.
Comment on
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Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy.Cancer Cell. 2016 Mar 14;29(3):270-284. doi: 10.1016/j.ccell.2016.02.003. Cancer Cell. 2016. PMID: 26977879 Free PMC article.
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