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. 2015:(8):30-3.

[THE ROLE OF NUTRITION IN THE GENESIS OF-HEPATIC OSTEODYSTROPHY IN PRIMARY BILIARY CIRRHOSIS]

[Article in Russian]
M K Prashnova, K L Raikhelson, O E Ivanova, L I Nazarenko, A Yu Baranovsky
  • PMID: 27017740

[THE ROLE OF NUTRITION IN THE GENESIS OF-HEPATIC OSTEODYSTROPHY IN PRIMARY BILIARY CIRRHOSIS]

[Article in Russian]
M K Prashnova et al. Eksp Klin Gastroenterol. 2015.

Abstract

The purpose: To evaluate the effect of diet on the development of hepatic osteodystrophy in patients with primary biliary cirrhosis.

Materials and methods: In 24 women with PBC, including signs of autoimmune hepatitis (PBC/AIH)--9 persons and 19 women in the control group were analyzed the daily diet, body composition, as well as bone mineral density in the lumbar spine and femur by dual-energy X-ray adsorbtsiometrii (DEXA).

The results: In PBC incidence of osteoporosis and severe osteoporosis was 22.7% and 9.1%, respectively, and osteopenia--59.1%, with a lesion predominantly lumbar spine. Inadequate intake of calcium in patients with PBC is associated with lower density of the femur. The high protein content in the diet has a protective effect on bone mineral density, associating with the development of osteopenia.

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