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Review
. 2016 May;241(9):899-908.
doi: 10.1177/1535370216640941. Epub 2016 Mar 27.

Rational design of fiber forming supramolecular structures

Vivek A Kumar  1 , Benjamin K Wang  2 , Satoko M Kanahara  3
Affiliations
Review

Rational design of fiber forming supramolecular structures

Vivek A Kumar et al. Exp Biol Med (Maywood). 2016 May.

Abstract

Recent strides in the development of multifunctional synthetic biomimetic materials through the self-assembly of multi-domain peptides and proteins over the past decade have been realized. Such engineered systems have wide-ranging application in bioengineering and medicine. This review focuses on fundamental fiber forming α-helical coiled-coil peptides, peptide amphiphiles, and amyloid-based self-assembling peptides; followed by higher order collagen- and elastin-mimetic peptides with an emphasis on chemical / biological characterization and biomimicry.

Keywords: Tissue engineering; elastin-mimetic peptides; peptide amphiphiles; peptide chemistry; supramolecular chemistry.

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