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Review
. 2016 Mar 26;8(3):101-5.
doi: 10.4252/wjsc.v8.i3.101.

Role of adipose-derived stromal cells in pedicle skin flap survival in experimental animal models

Pericles Foroglou  1 , Vasileios Karathanasis  1 , Efterpi Demiri  1 , George Koliakos  1 , Marios Papadakis  1
Affiliations
Review

Role of adipose-derived stromal cells in pedicle skin flap survival in experimental animal models

Pericles Foroglou et al. World J Stem Cells. .

Abstract

The use of skin flaps in reconstructive surgery is the first-line surgical treatment for the reconstruction of skin defects and is essentially considered the starting point of plastic surgery. Despite their excellent usability, their application includes general surgical risks or possible complications, the primary and most common is necrosis of the flap. To improve flap survival, researchers have used different methods, including the use of adipose-derived stem cells, with significant positive results. In our research we will report the use of adipose-derived stem cells in pedicle skin flap survival based on current literature on various experimental models in animals.

Keywords: Adipose stromal cells; Flap survival; Pedicle skin flap; Reconstructive surgery; Skin defect; Stem cell.

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