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. 2016 May;31(5):983-990.
doi: 10.1007/s00384-016-2568-8. Epub 2016 Mar 31.

Short-term mortality, readmission, and recurrence in treatment of acute diverticulitis with abscess formation: a nationwide register-based cohort study

Rasmus Gregersen  1   2 , Kristoffer Andresen  3   4 , Jakob Burcharth  3 , Hans-Christian Pommergaard  5 , Jacob Rosenberg  3   4
Affiliations

Short-term mortality, readmission, and recurrence in treatment of acute diverticulitis with abscess formation: a nationwide register-based cohort study

Rasmus Gregersen et al. Int J Colorectal Dis. 2016 May.

Abstract

Purpose: The aim of the study was to investigate short-term mortality, readmission, and recurrence in a national cohort of patients with Hinchey Ib-II diverticulitis.

Methods: The retrospective cohort-investigation was conducted using a database consisting of the entire Danish population (n = 6,641,672) in year 2000-2012, formed by linking the Danish Registers. Patients admitted with acute Hinchey Ib-II diverticulitis were identified from ICD-10 discharge codes and stratified according to treatment into an operative, drainage, and antibiotics group. The primary outcome was 30-day mortality from admission, secondary outcomes were mortality, readmission, and recurrence within 30 days post-discharge. The study was reported using RECORD guidelines.

Results: A total of 3148 eligible patients were identified. The cohort had a mean age of 65.1 year, 25.6 % had previously been admitted with diverticulitis, and 48.1 % had registered comorbidities. Within 30 days from admission, 8.7 % of the patients died. Of patients discharged, 2.5 % died, 23.8 % was readmitted, and 5.9 % was readmitted due to diverticulitis within 30 days from discharge. In multivariate analyses, increasing age was associated with mortality at odds-ratio (95 % CI) 1.10 (1.09-1.12). Previous complicated and uncomplicated diverticulitis reduced mortality with odds-ratio 0.50 (0.33-0.76) and 0.73 (0.58-0.92), while uncomplicated diverticulitis also increased risk of recurrence with odds-ratio 1.51 (1.24-1.84). Glucocorticoid usage was associated with mortality with odds-ratio 1.49 (1.23-1.81) and readmission with odds-ratio 2.91 (1.24-6.80).

Conclusion: Acute diverticulitis with abscess formation is a severe and life-threatening condition. Direct comparisons of treatment groups were not possible due to possible confounding by indication.

Keywords: Abscess; Complicated diverticulitis; Danish registers; Diverticulitis; Mortality; Readmission.

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References

    1. Gut. 2011 Feb;60(2):219-24 - PubMed
    1. Clin Epidemiol. 2015 Nov 17;7:449-90 - PubMed
    1. AJR Am J Roentgenol. 2006 Mar;186(3):680-6 - PubMed
    1. Dis Colon Rectum. 2005 Apr;48(4):787-91 - PubMed
    1. Am J Surg. 2012 Aug;204(2):172-9 - PubMed

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