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Case Reports
. 2016 Dec;36(4):404-407.
doi: 10.1097/WNO.0000000000000361.

Optic Neuropathy and Stroke Secondary to Invasive Aspergillus in an Immunocompetent Patient

Carrie M Hersh  1 , Seby John, Adnan Subei, Mary A Willis, Gregory S Kosmorsky, Richard A Prayson, Adarsh Bhimraj
Affiliations
Case Reports

Optic Neuropathy and Stroke Secondary to Invasive Aspergillus in an Immunocompetent Patient

Carrie M Hersh et al. J Neuroophthalmol. 2016 Dec.

Abstract

Angioinvasive aspergillosis is an aggressive fungal infection that is potentially life threatening without prompt treatment. Optic nerve involvement of Aspergillus can mimic optic neuritis commonly seen in demyelinating and other inflammatory conditions. Treatment of Aspergillus infection with steroids may worsen the clinical course. We describe a unique case of disseminated central nervous system aspergillosis, initially presenting as an optic neuropathy, with subsequent stroke in multiple vascular territories.

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