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. 1989 Mar;81(4):339-42.
doi: 10.1007/BF00283687.

Localization of human c-mos to chromosome band 8q11 in leukemic cells with the t(8;21) (q22;q22)

C M Morris  1 , J Bowen, P H Fitzgerald
Affiliations

Localization of human c-mos to chromosome band 8q11 in leukemic cells with the t(8;21) (q22;q22)

C M Morris et al. Hum Genet. 1989 Mar.

Abstract

Chromosome in situ hybridization studies locate c-mos to chromosome band 8q11 in leukemic cells carrying the t(8;21) (q22;q22). This amends the previous assignment of c-mos to chromosome band 8q22 and conforms with its recent assignment to 8q11 in normal cells and in a cell line with a structurally abnormal chromosome 8. C-mos lies proximally to, and distant from, the breakpoint at 8q22 in the t(8;21) and is unlikely to have a role in the onset of acute myeloid leukemia characterized by this translocation.

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