Review
doi: 10.1016/j.critrevonc.2016.03.016.
Epub 2016 Mar 25.
Mast cells in lymphomas
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- PMID: 27033307
- DOI: 10.1016/j.critrevonc.2016.03.016
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Review
Mast cells in lymphomas
Crit Rev Oncol Hematol.
2016 May.
Abstract
Tumor microenvironment is involved in the pathogenesis and progression of human lymphomas. The lymphoma microenvironment is composed by stromal cells, immune cells (macrophages, plasma cells, mast cells, eosinophils, basophils, T- and B-cells), blood vessels and extracellular matrix proteins. This article is focused on the role of mast cells in lymphoma progression and angiogenesis. Mast cells might be regarded in a future perspective as a new target for the adjuvant treatment of tumors, including lymphomas.
Keywords: Angiogenesis; Lymphoma; Mast cells; Tumor microenvironment; Tumor progression.
Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
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