Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Mar;42(3):250-3.
doi: 10.1136/jcp.42.3.250.

Clinical importance of squamous metaplasia in invasive transitional cell carcinoma of the bladder

J E Martin  1 , B J Jenkins, R J Zuk, J P Blandy, S I Baithun
Affiliations

Clinical importance of squamous metaplasia in invasive transitional cell carcinoma of the bladder

J E Martin et al. J Clin Pathol. 1989 Mar.

Abstract

One hundred cases of transitional cell carcinoma of the bladder were studied to determine whether squamous metaplasia and other histological features within the bladder can be of value in predicting outcome of treatment with radiotherapy. Sixty cases showed the changes of squamous metaplasia, and of this group 46 (78%) failed to respond to radiotherapy. A significant response rate of 90% was seen in the 40 tumours without squamous metaplasia. It is concluded that transitional cell carcinomas of the bladder showing squamous metaplasia are mainly resistant to radiotherapy and alternative treatment methods should be sought.

PubMed Disclaimer

Comment in

References

    1. Br J Urol. 1971 Feb;43(1):4-15 - PubMed
    1. Br J Urol. 1972 Aug;44(4):451-8 - PubMed
    1. Cancer. 1973 Nov;32(5):1267-74 - PubMed
    1. Cancer. 1977 Feb;39(2):447-55 - PubMed
    1. J Urol. 1980 May;123(5):644-52 - PubMed