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Review
. 2016 Apr 1;8(1):32.
doi: 10.1186/s13073-016-0287-y.

The virome: a missing component of biological interaction networks in health and disease

Scott A Handley  1
Affiliations
Review

The virome: a missing component of biological interaction networks in health and disease

Scott A Handley. Genome Med. .

Abstract

Host-associated viral populations, viromes, have been understudied relative to their contribution to human physiology. Viruses interact with host gene networks, influencing both health and disease. Analysis of host gene networks in the absence of virome analysis risks missing important network information.

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Figures

Fig. 1
Fig. 1
Examples of biological interaction networks. a Single data type network (for example, genes). Nodes are represented by circles, and edges (interactions) as black arrows. b Mixed-type biological network showing interactions between genes, proteins and species (for example, viruses, bacteria). Masked area (gray) indicates missing subgraph (for example, viral taxa)
See this image and copyright information in PMC

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