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Editorial
. 2016 Apr 19;315(15):1571-2.
doi: 10.1001/jama.2016.3670.

PCSK9 Inhibitors for Statin Intolerance?

Affiliations
Editorial

PCSK9 Inhibitors for Statin Intolerance?

David D Waters et al. JAMA. .
No abstract available

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Conflict of interest statement

Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Waters reported receiving personal fees from Sanofi-Aventis, Pfizer, Resverlogix, The Medicines Company, CSL Ltd, and Varicel. Dr Hsue reported receiving honoraria from Amgen, Gilead, Merck, and BMS and that she is planning a trial sponsored by Pfizer on PCSK9 inhibition with bococizumab. Dr Bangalore reported receiving personal fees from Pfizer.

Comment on

References

    1. Stroes ES, Thompson PD, Corsini A, et al. European Atherosclerosis Society Consensus Panel. Statin-associated muscle symptoms: impact on statin therapy—European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management. Eur Heart J. 2015;36(17):1012–1022. - PMC - PubMed
    1. Baigent C, Blackwell L, Emberson J, et al. Cholesterol Treatment Trialists' (CTT) Collaboration. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet. 2010;376(9753):1670–1681. - PMC - PubMed
    1. Zhang H, Plutzky J, Skentzos S, et al. Discontinuation of statins in routine care settings: a cohort study. Ann Intern Med. 2013;158(7):526–534. - PMC - PubMed
    1. Hovingh GK, Gandra SR, McKendrick J, et al. Identification and management of patients with statin-associated symptoms in clinical practice: a clinician survey. Atherosclerosis. 2016;245:111–117. - PubMed
    1. US Food and Drug Administration (FDA) FDA: Limit Use of 80 mg Simvastatin. [Accessed March 13, 2016]; FDA website. http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm257884.htm.

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