Progress Toward the Control and Management of the Thalassemias
- PMID: 27040959
- DOI: 10.1016/j.hoc.2015.12.001
Progress Toward the Control and Management of the Thalassemias
Abstract
Because of the particularly high frequency of different severe forms of both α and β thalassemia in Asia, the development of approaches for their prevention and management is particularly challenging. However, because of earlier partnerships with richer countries, so-called North/South partnerships, and help from their governments, considerable progress toward the better control of the thalassemias has been achieved in some countries. It is vital that the global health importance of the thalassemias and related disorders, by far the commonest genetic diseases, is emphasized to the appropriate international health agencies.
Keywords: Different forms of thalassemia; Management; National partnerships; Prevention; Role of non-governmental organizations; Screening.
Copyright © 2016 Elsevier Inc. All rights reserved.
Similar articles
-
Thalassemia as a global health problem: recent progress toward its control in the developing countries.Ann N Y Acad Sci. 2010 Aug;1202:17-23. doi: 10.1111/j.1749-6632.2010.05546.x. Ann N Y Acad Sci. 2010. PMID: 20712767
-
The Evolving Spectrum of the Epidemiology of Thalassemia.Hematol Oncol Clin North Am. 2018 Apr;32(2):165-175. doi: 10.1016/j.hoc.2017.11.008. Hematol Oncol Clin North Am. 2018. PMID: 29458724 Review.
-
Keynote address: The challenge of thalassemia for the developing countries.Ann N Y Acad Sci. 2005;1054:11-7. doi: 10.1196/annals.1345.002. Ann N Y Acad Sci. 2005. PMID: 16339646
-
Non-transfusion-dependent thalassemias.Haematologica. 2013 Jun;98(6):833-44. doi: 10.3324/haematol.2012.066845. Haematologica. 2013. PMID: 23729725 Free PMC article. Review.
-
Thalassemia: current approach to an old disease.Pediatr Clin North Am. 2002 Dec;49(6):1165-91, v. doi: 10.1016/s0031-3955(02)00088-3. Pediatr Clin North Am. 2002. PMID: 12580361 Review.
Cited by
-
Co-Treatment of Erythroid Cells from β-Thalassemia Patients with CRISPR-Cas9-Based β039-Globin Gene Editing and Induction of Fetal Hemoglobin.Genes (Basel). 2022 Sep 26;13(10):1727. doi: 10.3390/genes13101727. Genes (Basel). 2022. PMID: 36292612 Free PMC article.
-
Changing patterns in the epidemiology of β-thalassemia.Eur J Haematol. 2020 Dec;105(6):692-703. doi: 10.1111/ejh.13512. Epub 2020 Sep 21. Eur J Haematol. 2020. PMID: 32886826 Free PMC article. Review.
-
Combined approaches for increasing fetal hemoglobin (HbF) and de novo production of adult hemoglobin (HbA) in erythroid cells from β-thalassemia patients: treatment with HbF inducers and CRISPR-Cas9 based genome editing.Front Genome Ed. 2023 Jul 17;5:1204536. doi: 10.3389/fgeed.2023.1204536. eCollection 2023. Front Genome Ed. 2023. PMID: 37529398 Free PMC article. Review.
-
Frequency of unnecessary prenatal diagnosis of hemoglobinopathies: A large retrospective analysis and implication to improvement of the control program.PLoS One. 2023 Apr 14;18(4):e0283051. doi: 10.1371/journal.pone.0283051. eCollection 2023. PLoS One. 2023. PMID: 37058522 Free PMC article.
-
Feasibility of and barriers to thalassemia screening in migrant populations: a cross-sectional study of Myanmar and Cambodian migrants in Thailand.BMC Public Health. 2021 Jun 21;21(1):1177. doi: 10.1186/s12889-021-11059-2. BMC Public Health. 2021. PMID: 34154562 Free PMC article.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical