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Review
. 2016:2016:5187061.
doi: 10.1155/2016/5187061. Epub 2016 Mar 3.

Concomitant Thyroid Disorders and Inflammatory Bowel Disease: A Literature Review

Toru Shizuma  1
Affiliations
Review

Concomitant Thyroid Disorders and Inflammatory Bowel Disease: A Literature Review

Toru Shizuma. Biomed Res Int. 2016.

Abstract

The aim of this report was to review and summarize the literature on cases of concomitant inflammatory bowel disease (IBD) and thyroid diseases. We included the following previous case reports of concomitant IBD and thyroid diseases: 16 cases of ulcerative colitis (UC) and Graves' disease (GD), 3 cases of Crohn's disease (CD) and GD, 10 cases of CD and Hashimoto's thyroiditis (HT), 4 cases of IBD and subacute thyroiditis (SAT) or SAT-like symptoms, and 13 cases of IBD (12/13 cases were CD) and amyloid goiter. There might be no obvious differences of prevalence of thyroid dysfunction (hyper- or hypothyroidism), GD, and thyroid cancer between IBD patients and general populations. However, concomitant UC and HT might be relatively common in patients with multiple autoimmune disorders, and AG is one of the complications with CD patients. There might be no obvious differences of fatal prognoses between IBD patients with thyroid diseases and patients with thyroid diseases without IBD.

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References

    1. Fakhoury M., Negrulj R., Mooranian A., Al-Salami H. Inflammatory bowel disease: clinical aspects and treatments. Journal of Inflammation Research. 2014;7(1):113–120. doi: 10.2147/jir.s65979. - DOI - PMC - PubMed
    1. Triantafillidis J. K., Manoussakis C. A., Tsafaras C., Koutsorizof A. Coexistence of thyreotoxicosis and exacerbation of ulcerative colitis. The American Journal of Gastroenterology. 1990;85(7):908–910. - PubMed
    1. Triantafillidis J. K., Cherakakis A., Theororou M. Coexistence of hyperthyroidism and ulcerative colitis: report of 4 cases and a review of the literature. Italian Journal of Gastroenterology. 1992;24(9):494–497. - PubMed
    1. Radetti G. Clinical aspects of Hashimoto's thyroiditis. Endocrine Development. 2014;26:158–170. doi: 10.1159/000363162. - DOI - PubMed
    1. Casella G., De Marco E., Antonelli E., et al. The prevalence of hyper- and hypothyroidism in patients with ulcerative colitis. Journal of Crohn's and Colitis. 2008;2(4):327–330. doi: 10.1016/j.crohns.2008.09.001. - DOI - PubMed

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