Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Aug;30(4):637-43.
doi: 10.1007/s00540-016-2169-2. Epub 2016 Apr 4.

Preoperative serum lactate cannot predict in-hospital mortality after decompressive craniectomy in traumatic brain injury

Affiliations

Preoperative serum lactate cannot predict in-hospital mortality after decompressive craniectomy in traumatic brain injury

Youn Yi Jo et al. J Anesth. 2016 Aug.

Abstract

Purpose: Despite the utility of serum lactate for predicting clinical courses, little information is available on the topic after decompressive craniectomy. This study was conducted to determine the ability of perioperative serum lactate levels to predict in-hospital mortality in traumatic brain-injury patients who received emergency or urgent decompressive craniectomy.

Methods: The medical records of 586 consecutive patients who underwent emergency or urgent decompressive craniectomy due to traumatic brain injuries from January 2007 to December 2014 were retrospectively analyzed. Pre- and intraoperative serum lactate levels and base deficits were obtained from arterial blood gas analysis results.

Results: The overall mortality rate after decompressive craniectomy was 26.1 %. Mean preoperative serum lactate was significantly higher in the non-survivors (P = 0.034) than the survivors but had no significance for predicting in-hospital mortality in the multivariate regression analysis (P = 0.386). Rather, preoperative Glasgow Coma Score was a significant predictor for in-hospital mortality (hazard ratio 0.796, 95 % confidence interval 0.755-0.836, P < 0.001).

Conclusion: Preoperative lactate level is not an independent predictor of in-hospital mortality after decompressive craniectomy in traumatic brain-injury patients.

Keywords: Craniectomy; Mortality; Serum lactate; Traumatic brain injury.

PubMed Disclaimer

Similar articles

Cited by

References

    1. J Trauma. 1993 Oct;35(4):584-8; discussion 588-9 - PubMed
    1. Pediatr Radiol. 2005 Jul;35(7):668-76 - PubMed
    1. Acta Neurochir (Wien). 2015 Sep;157(8):1323-8 - PubMed
    1. J Neurosurg. 1988 Nov;69(5):736-44 - PubMed
    1. J Trauma. 2004 May;56(5):1084-9 - PubMed

LinkOut - more resources