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Case Reports
. 2016 Apr-Jun;21(2):75-7.
doi: 10.4103/0971-9261.172502.

Synovial sarcoma of kidney in a child: A rare presentation

Venkatraman Radhakrishnan  1 , Manikandan Dhanushkodi  1 , Kathiresan Narayanswamy  2 , Anand Raja  2 , Shirley Sundersingh  3 , Tenali Sagar  1
Affiliations
Case Reports

Synovial sarcoma of kidney in a child: A rare presentation

Venkatraman Radhakrishnan et al. J Indian Assoc Pediatr Surg. 2016 Apr-Jun.

Abstract

There are no reported cases in the literature of primary renal synovial sarcoma in pediatric patients. The management of renal synovial sarcoma has been extrapolated from the management of soft tissue sarcomas at other sites. We present a 4-year-old female who was suspected to have Wilms' tumor. The patient underwent guided biopsy as she did not respond to neoadjuvant chemotherapy for Wilms' tumor. The biopsy was consistent with primary renal synovial sarcoma. The child was treated with change in her neoadjuvant chemotherapy regimen and surgery. The diagnosis of synovial sarcoma was confirmed by demonstrating the t (X, 18) translocation using polymerase chain reaction.

Keywords: Chemotherapy; kidney; sarcoma.

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Figures

Figure 1
Figure 1
Computed tomographic (CT) scan of the abdomen at diagnosis showing a large right renal mass
Figure 2
Figure 2
After chemotherapy, the nephrectomy specimen shows residual tumor composed of spindle-shaped tumor cells admixed with groups of epithelioid tumor cells (H&E 100× magnification)
See this image and copyright information in PMC

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