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Case Reports
. 2013 Jan 11:12:1-4.
eCollection 2013.

Adrenal involvement in histoplasmosis

Norasyikin A Wahab  1 , Rozita Mohd  1 , Suehazlyn Zainudin  1 , Nor Azmi Kamaruddin  1
Affiliations
Case Reports

Adrenal involvement in histoplasmosis

Norasyikin A Wahab et al. EXCLI J. .

Abstract

Histoplasmosis infection is endemic in Asia and disseminated histoplasmosis (DH) is one form of its presentation (Benevides et al., 2007[1]). DH commonly affects both adrenal glands. We describe a case of disseminated histoplasmosis complicated with hypercalcaemia in a 75-year-old immunosuppressed patient who presented with bilateral adrenal masses. The fine needle aspiration cytology of the adrenal mass was positive for Histoplasma capsulatum.

Keywords: Histoplasma capsulatum; adrenal masses; disseminated histoplasmosis; hypoadrenalism.

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Figures

Figure 1
Figure 1. Axial computed tomography scan showed heterogenous enhancing bilateral adrenal enlargement (arrow) measuring 5.0 x 4.0 cm on the left (attenuation value, 30-40 HU) and 4 x 3.6 cm on the right (attenuation value, 40-50 HU) with peripheral enhancement and septations.
Figure 2
Figure 2. Sagital computed tomography scan showed heterogenous enhancing bilateral adrenal enlargement (arrow).
Figure 3
Figure 3. Histopathology of biopsy specimen from the left adrenal mass which showed numerous thin-walled rounded yeast liked bodies and some with budding (arrow), seen especially within the necrotic area (Grocott stain, x 1000).
See this image and copyright information in PMC

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