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Review
. 2016 Mar 24:6:63.
doi: 10.3389/fonc.2016.00063. eCollection 2016.

The Application and Outcome of Standard of Care Treatment in Elderly Women with Ovarian Cancer: A Literature Review over the Last 10 Years

Steven J Gibson  1 , Gini F Fleming  2 , Sarah M Temkin  3 , Dana M Chase  1
Affiliations
Review

The Application and Outcome of Standard of Care Treatment in Elderly Women with Ovarian Cancer: A Literature Review over the Last 10 Years

Steven J Gibson et al. Front Oncol. .

Abstract

The rising number and increasing longevity of the elderly population calls for improvements and potentially a more personalized approach to the treatment of cancer in this group. Elderly patients frequently present with a number of comorbidities, complicating surgery and chemotherapy tolerability. In the case of ovarian cancer, elderly women present with more advanced disease, making the issue of providing adequate treatment without significant morbidity critical. Most studies support the application of standard of care treatment to elderly women with ovarian cancer, yet it seems to be offered less frequently in the elderly. The objective of this review is to examine the application and outcome of standard of care treatment in elderly women with ovarian cancer. The aim is to ultimately improve the approach to treatment in this group.

Keywords: age; care; chemotherapy; elderly; outcomes; ovarian cancer; treatment.

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Figures

Figure 1
Figure 1
Relative survival rates by age in ovarian cancer patients over 20-year study period (8).
Figure 2
Figure 2
Primary surgical treatment for elderly women with ovarian cancer.
Figure 3
Figure 3
Summary of Selected Surveillance, Epidemiology and End Results (SEER) data (7, 10, 12, 54, 55).
See this image and copyright information in PMC

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