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Case Reports
. 2015 Dec 15;2(3):67-70.
doi: 10.1159/000442708. eCollection 2015 Jul-Dec.

Psammomatous Melanotic Schwannoma: A Challenging Histological Diagnosis

Rastine Merat  1 , Ildiko Szalay-Quinodoz  2 , Emmanuel Laffitte  1 , Gürkan Kaya  1
Affiliations
Case Reports

Psammomatous Melanotic Schwannoma: A Challenging Histological Diagnosis

Rastine Merat et al. Dermatopathology (Basel). .

Abstract

Psammomatous melanotic schwannoma (PMS) is a rare pigmented tumor that can be part of the Carney complex. Here, we describe the case of a 35-year-old female patient presenting an isolated subcutaneous PMS. Histopathological analysis could not formally exclude the malignant nature of the tumor. The challenging histological diagnosis and consequently the management of the patient are described.

Keywords: Melanoma; Psammoma bodies; Psammomatous melanotic schwannoma; Schwann cells.

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Figures

Fig. 1
Fig. 1
Well-circumscribed subcutaneous tumor (a, original magnification, ×0.2; b, original magnification, ×1) composed of spindle-shaped cells with frequent nuclear grooves (d, arrow; original magnification, ×82) and intracytoplasmic melanin pigment. Numerous psammoma bodies were present (c, arrow; original magnification, ×10).
Fig. 2
Fig. 2
The tumor cells were positive for S100 (a), Melan-A (b) and HMB-45 (c). Original magnification, ×10.
See this image and copyright information in PMC

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