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. 2016 Mar;32(1):65-9.
doi: 10.5625/lar.2016.32.1.65. Epub 2016 Mar 24.

Anticoccidial effects of the Plantago asiatica extract on experimental Eimeria tenella infection

Sunhwa Hong  1 , Gi-Wook Oh  2 , Won-Guk Kang  2 , Okjin Kim  2
Affiliations

Anticoccidial effects of the Plantago asiatica extract on experimental Eimeria tenella infection

Sunhwa Hong et al. Lab Anim Res. 2016 Mar.

Abstract

Anticoccidial effects of the Plantago asiatica extract (PAE) were evaluated in chickens following oral infection with Eimeria (E.) tenella. This study was conducted on the 3-day-old chickens (n=30). Those animals were divided with 3 groups; PAE 0.1% treated/infected (n=10), PAE untreated/infected (n=10) and non-infected control (n=10). Chickens were fed a standard diet supplemented with or without PAE for 1 week prior to infection with E. tenella (10,000 sporulated oocysts per chicken). The effects of PAE on E. tenella infection were assessed by two parameters; fecal oocysts shedding and body weights gain. The PAE-fed chickens produced significantly reduced fecal oocysts (P<0.05) when compared to the E. tenella-infected group fed standard diet. Also, PAE-based diet, improved body weight loss caused by E. tenella infection. Our data demonstrated that PAE had remarkable anticoccidial activities against E. tenella. This finding might have implications for the development of anticoccidial drug. This study is the first to demonstrate anticoccidial effect of PAE on Eimeria parasites.

Keywords: Anticoccidial activity; Plantago asiatica; antiprotozoa; eimeria; eimeria tenella.

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Conflict of interest statement

Conflict of interests: The authors declare that there is no financial conflict of interests to publish these results.

Figures

Figure 1
Figure 1. Structures of PhGs extracted from P. asiatica. (1) Plantamajosides, R1=Rham; (2) acteoside, R1=Glc.
See this image and copyright information in PMC

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