Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2015 Nov 24;1(6):S33-5.
doi: 10.1016/j.jdcr.2015.09.019. eCollection 2015 Nov.

Two cases of trichodysplasia spinulosa responsive to compounded topical cidofovir 3% cream

Justin J Leitenberger  1 , Mark Abdelmalek  2 , Richard C Wang  3 , Lynne Strasfeld  4 , R Sam Hopkins  1
Affiliations
Case Reports

Two cases of trichodysplasia spinulosa responsive to compounded topical cidofovir 3% cream

Justin J Leitenberger et al. JAAD Case Rep. .
No abstract available

Keywords: TS, trichodysplasia spinulosa; TSPyV, trichodysplasia spinulosa polyomavirus; cidofovir 3% cream; hematologic malignancies; solid organ transplantation; trichodysplasia spinulosa.

PubMed Disclaimer

Figures

Fig 1
Fig 1
A, Presentation of multiple follicular spines, madarosis, and leonine facies. B, Smoother skin in affected areas after topical cidofovir 3% cream twice daily for 3 months.
Fig 2
Fig 2
A, Diffuse small hyperpigmented papules with spiny projections. B, Resolution of lesions with smoother skin after 2 months of twice-daily topical cidofovir 3% cream.
Fig 3
Fig 3
Histopathology of TS with increased cellularity of nucleated eosinophilic inner root sheath cells with trichohyalin granules.
See this image and copyright information in PMC

References

    1. Siebrasse E.A., Bauer I., Holtz L.R. Human polyomaviruses in children undergoing transplantation, United States, 2008-2010. Emerg Infect Dis. 2012;18:1676–1679. - PMC - PubMed
    1. Celeiro-Munoz C., Gonzalez-Vilas D., Sanchez-Aguilar D., Suarez-Penaranda J.M. Viral-associated trichodysplasia secondary to antineoplastic treatment in a patient with lymphoblastic leukemia. Am J Dermatopathol. 2014;36:e105–e107. - PubMed
    1. Sperling L.C., Tomaszewski M.M., Thomas D.A. Viral-associated trichodysplasia in patients who are immunocompromised. J Am Acad Dermatol. 2004;50:318–322. - PubMed
    1. Wyatt A.J., Sachs D.L., Shia J., Delgado R., Busam K.J. Virus-associated trichodysplasia spinulosa. Am J Surg Pathol. 2005;29:241–246. - PubMed
    1. Izakovic J., Buchner S.A., Duggelin M., Guggenheim R., Itin P.H. Hair-like hyperkeratoses in patients with kidney transplants. A new cyclosporin side-effect. Hautarzt. 1995;46:841–846. - PubMed

Publication types

LinkOut - more resources