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Review
. 2016 Sep-Oct;20(5):502-4.
doi: 10.1016/j.bjid.2016.03.002. Epub 2016 Apr 4.

Abacavir-induced liver toxicity

Maria Diletta Pezzani  1 , Chiara Resnati  1 , Valentina Di Cristo  1 , Agostino Riva  2 , Cristina Gervasoni  3
Affiliations
Review

Abacavir-induced liver toxicity

Maria Diletta Pezzani et al. Braz J Infect Dis. 2016 Sep-Oct.

Abstract

Abacavir-induced liver toxicity is a rare event almost exclusively occurring in HLA B*5701-positive patients. Herein, we report one case of abnormal liver function tests occurring in a young HLA B*5701-negative woman on a stable nevirapine-based regimen with no history of liver problems or alcohol abuse after switching to abacavir from tenofovir. We also investigated the reasons for abacavir discontinuation in a cohort of patients treated with abacavir-lamivudine-nevirapine.

Keywords: Abacavir; HIV; Liver toxicity.

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