doi: 10.1111/j.1600-0404.1978.tb04508.x.
Reversibility of the blood-brain barrier dysfunction induced by acute hypertension
- PMID: 27056
- DOI: 10.1111/j.1600-0404.1978.tb04508.x
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Reversibility of the blood-brain barrier dysfunction induced by acute hypertension
Acta Neurol Scand.
1978 Apr.
Abstract
An acute hypertensive episode of short duration (less than 3 min) induced by i.v. injection of angiotensin in rats resulted in a blood-brain barrier dysfunction that was rapidly reversible. Thus, no macroscopic extravasation was seen when Evans blue was given 10 or 20 min after angiotensin. A faint fluorescence (Evans blue-albumin) was seen in the walls of some intracerebral arterioles in a few rats given the tracer 10 min after angiotensin.
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