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Editorial
. 2016 Jul-Aug;78(6):642-5.
doi: 10.1097/PSY.0000000000000329.

Multiplexing and Beyond in Biobehavioral Research

Paul J Mills  1 , Christine T Peterson
Affiliations
Editorial

Multiplexing and Beyond in Biobehavioral Research

Paul J Mills et al. Psychosom Med. 2016 Jul-Aug.

Abstract

In contrast to traditional singleplex assays that provide values for only a single analyte in a single biological sample, multiplex assays are a time- and resource-efficient high-throughput approach that provides the opportunity to determine numerous analytes within a single- and small-sample volume. In this editorial on an article by Dorn et al. in this issue of Psychosomatic Medicine, we provide a brief description of the advantages and challenges related to multiplex assays. Although the use of multiplexing as a tool has been relatively limited in biobehavioral research, more recent studies are taking advantage of this technology to obtain deeper insight into regulatory patterns in health and disease states. Multiplex approaches range from several targets to global target profiling that importantly enable unbiased biomarker and pathway discovery.

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Figures

Figure 1.
Figure 1.
Number of publications appearing in PubMed by 5-year increments from 1975 to the present using the search terms “multiplexing, assay, biomarker”.
See this image and copyright information in PMC

Comment on

References

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