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. 2016 Apr;95(14):e3304.
doi: 10.1097/MD.0000000000003304.

Epidemiology of Postherpetic Neuralgia in Korea: An Electronic Population Health Insurance System Based Study

Myong-Joo Hong  1 , Yeon-Dong Kim, Yong-Kwan Cheong, Seon-Jeong Park, Seung-Won Choi, Hyon-Joo Hong
Affiliations

Epidemiology of Postherpetic Neuralgia in Korea: An Electronic Population Health Insurance System Based Study

Myong-Joo Hong et al. Medicine (Baltimore). 2016 Apr.

Abstract

Postherpetic neuralgia (PHN) is a disease entity defined as persistent pain after the acute pain of herpes zoster gradually resolves. It is associated with impaired daily activities, resulting in reduced quality of life. General epidemiological data on PHN is necessary for the effective management. However, data on the epidemiology of PHN in Korea is lacking. The aim of this study was to evaluate the epidemiological features of PHN in the general population.We used population-based medical data for 51,448,491 subscribers to the Health Insurance Service in the year of 2013 to analyze of PHN epidemiology in Korea, such as the incidence, regional distribution, seasonal variation, and healthcare resource utilization. Total number of patients and medical cost on PHN were analyzed from 2009 to 2013.Findings indicate that the incidence of PHN in Korea was 2.5 per 1000 person-years, which was strongly correlated with age and sex. There were no differences in seasonal variation or regional distribution. The medical cost increased steadily over the study period. When admitted to general hospitals, patients with PHN were mainly managed in the dermatology and anesthesiology departments.The incidence and prevalence rates of PHN in Koreans appear to be considerably higher compared to those in western populations, while the sex and age predisposition was similar. Considering that the pain associated with PHN can have a marked impact on a patient's quality of life resulting in a medicosocial economic burden, anesthesiology physicians have an important role in primary care in Korea. Future research on the cost-effectiveness of the management of PHN is needed.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

FIGURE 1
FIGURE 1
Incidence of postherpetic neuralgia in Korea in 2013.
FIGURE 2
FIGURE 2
Regional distribution of postherpetic neuralgia in Korea in 2013.
FIGURE 3
FIGURE 3
Total number of patients and medical cost of postherpetic neuralgia from 2009 to 2013.
FIGURE 4
FIGURE 4
Healthcare resource utilization of patients with postherpetic neuralgia in 2013 by medical specialty. PHCF = primary healthcare facilities.
See this image and copyright information in PMC

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