Stem Cells Expand Insights into Human Brain Evolution
- PMID: 27058930
- DOI: 10.1016/j.stem.2016.03.017
Stem Cells Expand Insights into Human Brain Evolution
Abstract
Substantial expansion in the number of cerebral cortex neurons is thought to underlie cognitive differences between humans and other primates, although the mechanisms underlying this expansion are unclear. Otani et al. (2016) utilize PSC-derived brain organoids to study how species-specific differences in cortical progenitor proliferation may underlie cortical evolution.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size.Cell Stem Cell. 2016 Apr 7;18(4):467-80. doi: 10.1016/j.stem.2016.03.003. Epub 2016 Mar 31. Cell Stem Cell. 2016. PMID: 27049876 Free PMC article.
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