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. 2016 Apr 7;18(4):425-6.
doi: 10.1016/j.stem.2016.03.017.

Stem Cells Expand Insights into Human Brain Evolution

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Stem Cells Expand Insights into Human Brain Evolution

Michael A Dyer. Cell Stem Cell. .
Free article

Abstract

Substantial expansion in the number of cerebral cortex neurons is thought to underlie cognitive differences between humans and other primates, although the mechanisms underlying this expansion are unclear. Otani et al. (2016) utilize PSC-derived brain organoids to study how species-specific differences in cortical progenitor proliferation may underlie cortical evolution.

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