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Review
. 2016 Apr;109(4):141-6.
doi: 10.1177/0141076816636369.

Advances in pancreas transplantation

Shamik Dholakia  1 , Youssof Oskrochi  2 , Graham Easton  2 , Vassilios Papalois  3
Affiliations
Review

Advances in pancreas transplantation

Shamik Dholakia et al. J R Soc Med. 2016 Apr.

Abstract

The potential to reverse diabetes has to be balanced against the morbidity of long-term immunosuppression associated with transplantation. For a patient with renal failure, the treatment of choice is often a simultaneous transplant of the pancreas and kidney or pancreas after kidney. For a patient with glycaemic instability, choices between a solid organ or islet transplant have to be weighed against benefits and risks of remaining on insulin. Results of simultaneous transplant of the pancreas and kidney transplantation are comparable to other solid-organ transplants, and there is evidence of improved quality of life and life expectancy. There is some evidence of benefit with respect to the progression of secondary diabetic complications in patients with functioning transplants for several years.

Keywords: Chronic diseases; endocrinology; evidence-based practice; surgery.

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Figures

Figure 1.
Figure 1.
Solid organ pancreas with vessel extension and diagramatic representation of operation.
See this image and copyright information in PMC

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