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Review
. 2016 May;20(2):225-43.
doi: 10.1016/j.cld.2015.10.002. Epub 2015 Dec 14.

The Metabolic Syndrome and Its Influence on Nonalcoholic Steatohepatitis

Affiliations
Review

The Metabolic Syndrome and Its Influence on Nonalcoholic Steatohepatitis

Pushpjeet Kanwar et al. Clin Liver Dis. 2016 May.

Abstract

Nonalcoholic steatohepatitis (NASH) and the metabolic syndrome (MetS) are highly prevalent in the Western population. Their pathogenesis is closely linked to insulin resistance, which serves as a therapeutic target for the management of these conditions. This review article reviews the research supporting the influence of MetS on NASH and includes studies supporting their similar epidemiology, pathogenesis, and treatment.

Keywords: Hepatocellular carcinoma; Metabolic syndrome; NAFLD; Nonalcoholic steatohepatitis; Risk factors.

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