Outbreak of ovine congenital toxoplasmosis in Iran, confirmed by different diagnostic methods

doi:10.1007/s12639-014-0467-x

. 2016 Mar;40(1):152-6.

doi: 10.1007/s12639-014-0467-x. Epub 2014 Apr 26.

Outbreak of ovine congenital toxoplasmosis in Iran, confirmed by different diagnostic methods

Ahmad Reza Movassaghi¹, Maryam Rassouli², Asghar Fazaeli³, Mohammad Reza Salimi-Bejestani⁴

Affiliations

¹ Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran ; Center of Excellence in Ruminant Abortion and Neonatal Mortality, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
² Pathobiology Department, Shahmirzad School of Veterinary Medicine, Semnan University, Vali Asr area, Shahmirzad, P.O.Box: 35718-95589, Semnan, Iran.
³ Department of Medical Parasitology & Entomology, Medical School, Zanjan University of Medical Sciences & Health Services, Zanjan, Iran.
⁴ Pathobiology Department, Veterinary Medicine Faculty, Semnan University, Semnan, Iran.

PMID: 27065616
PMCID: PMC4815860
DOI: 10.1007/s12639-014-0467-x

Outbreak of ovine congenital toxoplasmosis in Iran, confirmed by different diagnostic methods

Ahmad Reza Movassaghi et al. J Parasit Dis. 2016 Mar.

. 2016 Mar;40(1):152-6.

doi: 10.1007/s12639-014-0467-x. Epub 2014 Apr 26.

Authors

Ahmad Reza Movassaghi¹, Maryam Rassouli², Asghar Fazaeli³, Mohammad Reza Salimi-Bejestani⁴

Affiliations

¹ Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran ; Center of Excellence in Ruminant Abortion and Neonatal Mortality, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
² Pathobiology Department, Shahmirzad School of Veterinary Medicine, Semnan University, Vali Asr area, Shahmirzad, P.O.Box: 35718-95589, Semnan, Iran.
³ Department of Medical Parasitology & Entomology, Medical School, Zanjan University of Medical Sciences & Health Services, Zanjan, Iran.
⁴ Pathobiology Department, Veterinary Medicine Faculty, Semnan University, Semnan, Iran.

PMID: 27065616
PMCID: PMC4815860
DOI: 10.1007/s12639-014-0467-x

Abstract

Toxoplasma gondii is a zoonotic obligatory intracellular protozoan parasite with the capability to infect all warm-blooded animals. One of the great concerns is that it can lead to ovine abortion in sheep growing industry. Different diagnostic methods such as serology, pathology, immunohistochemistry, bioassay and molecular detection have been used in order to detect ovine abortion associated with T. gondii. In this case, an outbreak of congenital toxoplasmosis based on serological, macroscopic, pathological detection and isolation of T. gondii by bioassay is described and emphasized on the importance of this route of transmission that caused lamb losses and an increase in possible sources of infection for human and environment.

Keywords: Iran; Outbreak; Ovine abortion; Toxoplasma gondii.

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Figures

**Fig. 1**
Brain tissue: severe hemorrhage, stained by H&E. 10×

**Fig. 2**
Brain tissue: a edema and hyperemia, b *Toxoplasma gondii* tissue cyst. Stained by H&E. 20×

**Fig. 3**
*Toxoplasma gondii* tissue cyst. Stained by H&E. 40×

See this image and copyright information in PMC

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References

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[1] Blewett DA, Watson WA. The epidemiology of ovine toxoplasmosis. II. Possible sources of infection in outbreaks of clinical disease. British Vet J. 1983;139:546–555. - PubMed

[2] Blewett DA, Watson WA. The epidemiology of ovine toxoplasmosis. II. Possible sources of infection in outbreaks of clinical disease. British Vet J. 1983;139:546–555. - PubMed

[3] Buxton D. Ovine toxoplasmosis: a review. J Royal Soc Med. 1990;83:509–511. - PMC - PubMed

[4] Buxton D. Ovine toxoplasmosis: a review. J Royal Soc Med. 1990;83:509–511. - PMC - PubMed

[5] Buxton D. Toxoplasmosis. In: Martin WB, Aitken ID, editors. Diseases of sheep. 2. Oxford: Blackwell Scientific Publications; 1991. pp. 49–58.

[6] Buxton D. Toxoplasmosis. In: Martin WB, Aitken ID, editors. Diseases of sheep. 2. Oxford: Blackwell Scientific Publications; 1991. pp. 49–58.

[7] Buxton D (2008) Toxoplasmosis. OIE terrestrial manual. Vol 2, Chapter 2.9.10. CABI Publishing, Oxon, p 1284–1293

[8] Buxton D (2008) Toxoplasmosis. OIE terrestrial manual. Vol 2, Chapter 2.9.10. CABI Publishing, Oxon, p 1284–1293

[9] Dubey JP. Toxoplasmosis in sheep-the last 20 years. Vet Parasitol. 2009;163:1–14. doi: 10.1016/j.vetpar.2009.02.026. - DOI - PubMed

[10] Dubey JP. Toxoplasmosis in sheep-the last 20 years. Vet Parasitol. 2009;163:1–14. doi: 10.1016/j.vetpar.2009.02.026. - DOI - PubMed

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Outbreak of ovine congenital toxoplasmosis in Iran, confirmed by different diagnostic methods

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Outbreak of ovine congenital toxoplasmosis in Iran, confirmed by different diagnostic methods

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