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. 1977 Oct;74(10):4130-4.
doi: 10.1073/pnas.74.10.4130.

Structure of proteins: packing of alpha-helices and pleated sheets

C Chothia, M Levitt, D Richardson

Structure of proteins: packing of alpha-helices and pleated sheets

C Chothia et al. Proc Natl Acad Sci U S A. 1977 Oct.

Abstract

Simple models are presented that describe the rules for almost all the packing that occurs between and among alpha-helices and pleated sheets. These packing rules, together with the primary and secondary structures, are the major determinants of the three-dimensional structure of proteins.

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