Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016:2016:9176273.
doi: 10.1155/2016/9176273. Epub 2016 Mar 15.

In Vitro Antibacterial Spectrum of Sodium Selenite against Selected Human Pathogenic Bacterial Strains

Mohammad Firoz Alam  1 , Mohammed M Safhi  1 , Sivakumar Sivagurunathan Moni  2 , Aamena Jabeen  2
Affiliations

In Vitro Antibacterial Spectrum of Sodium Selenite against Selected Human Pathogenic Bacterial Strains

Mohammad Firoz Alam et al. Scientifica (Cairo). 2016.

Abstract

The objective of this investigation was to predict the antibacterial properties of sodium selenite against selected human pathogens. A group of six human bacterial pathogens including Staphylococcus aureus, Streptococcus pyogenes, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, and Klebsiella planticola were utilized for screening. The spectrum of activity was qualified based on zone of inhibition. Our study demonstrated that sodium selenite exhibits a strong spectrum of activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Klebsiella planticola. The spectrum of activity was compared with standard ciprofloxacin disc (5 μg/disc) and observed to have satisfactory effect.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Significant spectrum of activity of sodium selenite when compared to standard ciprofloxacin, ∗ P < 0.05 sodium selenite when compared to ciprofloxacin in Bacillus subtilis and ∗∗ P < 0.01 sodium selenite when compared to ciprofloxacin in Klebsiella planticola.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Thirunavukkarasu C., Premkumar K., Sheriff A. K., Sakthisekaran D. Sodium selenite enhances glutathione peroxidase activity and DNA strand breaks in hepatoma induced by N-nitrosodiethylamine and promoted by phenobarbital. Molecular and Cellular Biochemistry. 2008;310(1-2):129–139. doi: 10.1007/s11010-007-9673-5. - DOI - PubMed
    1. Berggren M., Sittadjody S., Song Z., Samira J.-L., Burd R., Meuillet E. J. Sodium selenite increases the activity of the tumor suppressor protein, PTEN, in DU-145 prostate cancer cells. Nutrition and Cancer. 2009;61(3):322–331. doi: 10.1080/01635580802521338. - DOI - PMC - PubMed
    1. Bernd E. L. Ullmann's Encyclopedia of Industrial Chemistry. Weinheim, Germany: Wiley-VCH; 2002. Selenium and selenium compounds.
    1. Schwarz K., Foltz C. M. Selenium as an integral part of factor-3 against dietary necrotic liver degeneration. Journal of the American Chemical Society. 1957;79(12):3292–3293.
    1. Maryland H. Selenium in plant and animal nutrition. In: Frankenberger W. T., Benson S., editors. Selenium in the Environment. New York, NY, USA: Marcel Dekker; 1994. pp. 29–45.

LinkOut - more resources