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. 2016 Jan 26;2016(1):CD012055.
doi: 10.1002/14651858.CD012055.

Alternative agents versus prophylactic platelet transfusion for preventing bleeding in patients with thrombocytopenia due to chronic bone marrow failure: a network meta-analysis and systematic review

Michael Desborough  1 , Lise J Estcourt  1 , Anna Chaimani  2 , Carolyn Doree  3 , Sally Hopewell  4 , Marialena Trivella  5 , Andreas V Hadjinicolaou  6 , Paresh Vyas  7 , Simon J Stanworth  8
Affiliations

Alternative agents versus prophylactic platelet transfusion for preventing bleeding in patients with thrombocytopenia due to chronic bone marrow failure: a network meta-analysis and systematic review

Michael Desborough et al. Cochrane Database Syst Rev. .

Update in

Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows: To compare the relative efficacy of different treatments for thrombocytopenia (artificial platelet substitutes, platelet-poor plasma, fibrinogen, rFVIIa, rFXIII, thrombopoietin mimetics, antifibrinolytic drugs or platelet transfusions) in patients with chronic bone marrow failure and to derive a hierarchy of potential alternate treatments to platelet transfusions.

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Figures

<b>Figure 1</b>
Figure 1. Network graph demonstrating all possible pairwise comparisons. DDAVP - desmopressin, EACA - epsilon aminocaproic acid, PPP - platelet poor plasma, rFVIIa - recombinant activated factor VII, rFXIII - recombinant factor XIII, rIL-6 - recombinant interleukin 6, IL-11 - recombinant interleukin 11 and TXA - tranexamic acid
See this image and copyright information in PMC

References

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