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. 2016 Jun;22(6):1129-31.
doi: 10.3201/eid2206.152113. Epub 2016 Jun 15.

MERS-CoV Infection of Alpaca in a Region Where MERS-CoV is Endemic

Chantal B E M Reusken, Chrispijn Schilp, V Stalin Raj, Erwin De Bruin, Robert H G Kohl, Elmoubasher A B A Farag, Bart L Haagmans, Hamad Al-Romaihi, Francois Le Grange, Berend-Jan Bosch, Marion P G Koopmans

MERS-CoV Infection of Alpaca in a Region Where MERS-CoV is Endemic

Chantal B E M Reusken et al. Emerg Infect Dis. 2016 Jun.
No abstract available

Keywords: MERS-CoV; Middle East respiratory syndrome coronavirus; Qatar; SARS-CoV; Vicugna pacos; alpaca; camelid; dromedary; severe acute respiratory syndrome coronavirus; viruses; zoonoses.

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Figures

Figure
Figure
Column scatterplots of MERS-CoV reactivity of serum samples from alpaca (n = 15) and dromedaries (n = 10) in the Al Shahaniya region of Qatar, April 2015. A) Plot of alpaca and dromedary serum titers of antibodies specific for S1 antigens of 2 coronaviruses as determined by protein microarray. Titers were defined as the interpolated serum concentration that provoked a response half-way on a concentration-response curve between the minimum and maximum signal and were calculated from the inflection point of a 4-step dilution series (1:20 to 1:1,280) as described previously (5). B) Plot of alpaca and dromedary serum titers of MERS-CoV neutralizing antibodies as determined by PRNT90. The highest serum dilution neutralizing 90% of plaque formation is depicted. For both panels, solid lines indicate median, and dotted lines indicate detection limit. MERS, Middle East respiratory syndrome; CoV, coronavirus; PRNT90, 90% plaque-reduction neutralization test; SARS, severe acute respiratory syndrome.
See this image and copyright information in PMC

References

    1. Chan JF, Lau SK, To KK, Cheng VC, Woo PC, Yuen KY. Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease. Clin Microbiol Rev. 2015;28:465–522. 10.1128/CMR.00102-14 - DOI - PMC - PubMed
    1. Haagmans BL, Al Dhahiry SH, Reusken CB, Raj VS, Galiano M, Myers R, et al. Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation. Lancet Infect Dis. 2014;14:140–5. - PMC - PubMed
    1. Reusken CB, Farag EA, Haagmans BL, Mohran KA, Godeke GJVV, Raj S, et al. Occupational exposure to dromedaries and risk for MERS-CoV infection, Qatar, 2013–2014. Emerg Infect Dis. 2015;21:1422–5. 10.3201/eid2108.150481 - DOI - PMC - PubMed
    1. Reusken CB, Haagmans BL, Müller MA, Gutierrez C, Godeke GJ, Meyer B, et al. Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study. Lancet Infect Dis. 2013;13:859–66. 10.1016/S1473-3099(13)70164-6 - DOI - PMC - PubMed
    1. Koopmans M, de Bruin E, Godeke GJ, Friesema I, van Gageldonk R, Schipper M, et al. Profiling of humoral immune responses to influenza viruses by using protein microarray. Clin Microbiol Infect. 2012;18:797–807. 10.1111/j.1469-0691.2011.03701.x - DOI - PubMed

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