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Observational Study
. 2016 Apr 14:26:16016.
doi: 10.1038/npjpcrm.2016.16.

Are pharmacological randomised controlled clinical trials relevant to real-life asthma populations? A protocol for an UNLOCK study from the IPCRG

Karin Lisspers  1 , Pedro Teixeira  2 , Coert Blom  3 , Janwillem Kocks  4   5 , Björn Ställberg  1 , David Price  6 , Niels Chavannes  7
Affiliations
Observational Study

Are pharmacological randomised controlled clinical trials relevant to real-life asthma populations? A protocol for an UNLOCK study from the IPCRG

Karin Lisspers et al. NPJ Prim Care Respir Med. .
No abstract available

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Conflict of interest statement

JK, BS and NC are Associate Editors of npj Primary Care Respiratory Medicine, but were not involved in the editorial review of, nor the decision to publish this article. KL has received honoraria for educational activities and lectures from AstraZeneca, GlaxoSmithKline, Novartis, MEDA and Takeda, and has served on advisory boards arranged by MEDA and Novartis. BS has received honoraria for educational activities and lectures from AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline, Novartis, MEDA and TEVA, and has served on advisory boards arranged by AstraZeneca, Novartis and Boehringer Ingelheim. DBP has Board Membership with Aerocrine, Almirall, Amgen, AstraZeneca, Boehringer Ingelheim, Chiesi, Meda, Mundipharma, Napp, Novartis and Teva. Consultancy: Almirall, Amgen, AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Meda, Mundipharma, Napp, Novartis, Pfizer, Teva and Zentiva; grants/grants pending with UK National Health Service, British Lung Foundation, Aerocrine, AstraZeneca, Boehringer Ingelheim, Chiesi, Eli Lilly, GlaxoSmithKline, Meda, Merck, Mundipharma, Novartis, Orion, Pfizer, Respiratory. Effectiveness Group, Takeda, Teva and Zentiva; payments for lectures/speaking: Almirall, AstraZeneca, Boehringer Ingelheim, Chiesi, Cipla, GlaxoSmithKline, Kyorin, Meda, Merck, Mundipharma, Novartis, Pfizer, SkyePharma, Takeda and Teva; payment for manuscript preparation: Mundipharma and Teva; patents (planned, pending, or issued): AKL; payment for the development of educational materials: GlaxoSmithKline, Novartis; stock/stock options: shares in AKL that produces phytopharmaceuticals and owns 80% of Research in Real-Life and its subsidiary social enterprise Optimum Patient Care; received payment for travel/accommodations/meeting expenses from Aerocrine, Boehringer Ingelheim, Mundipharma, Napp, Novartis, and Teva; funding for patient enrollment or completion of research: Almirall, Chiesi, Teva and Zentiva; peer reviewer for grant committees: Medical Research Council (2014), Efficacy and Mechanism Evaluation programme (2012), HTA (2014); and received unrestricted funding for investigator-initiated studies from Aerocrine, AKL, Almirall, Boehringer Ingelheim, Chiesi, Meda, Mundipharma, Napp, Novartis, Orion, Takeda, Teva and Zentiva. The remaining authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Flowchart of RCT identification process.
See this image and copyright information in PMC

References

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