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. 1977 Nov;74(11):5131-4.
doi: 10.1073/pnas.74.11.5131.

Chemical characterization of murine Ia alloantigens determined by the i-E/i-C subregions of the H-2 complex

J Silver, W A Russell, B L Reis, J A Frelinger

Chemical characterization of murine Ia alloantigens determined by the i-E/i-C subregions of the H-2 complex

J Silver et al. Proc Natl Acad Sci U S A. 1977 Nov.

Abstract

Alloantisera directed against the alloantigens determined by the I-E and I-C subregions of the murine major histocompatibility complex precipitate two components that have molecular weights of 35,000 and 29,000. These components, when analyzed by partial NH2-terminal sequencing, show no homology to two components of similar size determined by the I-A subregion. However, the large chain determined by the murine I-E and/or I-C subregion is homologous to the large chain of the human HLA-D region alloantigen, although the small chains isolated from these two species do not display any such homology.

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References

    1. Cold Spring Harb Symp Quant Biol. 1977;41 Pt 1:387-96 - PubMed
    1. Cold Spring Harb Symp Quant Biol. 1977;41 Pt 1:379-86 - PubMed
    1. Cold Spring Harb Symp Quant Biol. 1977;41 Pt 2:443-55 - PubMed
    1. Transplant Proc. 1977 Mar;9(1):393-400 - PubMed
    1. Transplant Proc. 1977 Mar;9(1):661-5 - PubMed