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Case Reports
. 2014 Oct 5;1(1):15-7.
doi: 10.1016/j.jdcr.2014.10.002. eCollection 2015 Jan.

Interferon beta-1a-induced morphea

Spencer A Bezalel  1 , Bruce E Strober  2 , Katalin Ferenczi  3
Affiliations
Case Reports

Interferon beta-1a-induced morphea

Spencer A Bezalel et al. JAAD Case Rep. .
No abstract available

Keywords: IFN-β, Interferon beta; IFN-β1a, Interferon beta-1a; IL-4, Interleukin 4; MS, Multiple sclerosis; SSc, Systemic sclerosis; Th2, T helper 2; injection site reaction; interferon beta-1a; morphea; multiple sclerosis.

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Figures

Fig 1
Fig 1
Depressed, indurated, bound-down hyperpigmented plaques involving anterior thighs (A) and right hip (B).
Fig 2
Fig 2
A, Punch biopsy from the right thigh shows thickened collagen bundles extending into the subcutaneous fat, paucity of adnexal structures, and a deep reticular lymphocytic infiltrate (Hematoxylin-eosin stain; original magnification: ×4). B, Higher magnification image shows thickened collagen, lymphoplasmacytic infiltrate, and entrapment of the eccrine glands by collagen (original magnification: ×20).
See this image and copyright information in PMC

References

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    1. Sartori-Valinotti J., Tollefson M.M., Reed A.M. Updates on Morphea: Role of Vascular Injury and Advances in Treatment. Autoimmune Dis. 2013;2013:1–8. - PMC - PubMed
    1. Grabell D., Clifford H., Andrew R. The role of skin trauma in the distribution of morphea lesions: A cross-sectional survey of the Morphea in Adults and Children cohort IV. J Am Acad Dermatol. 2014;71:493–498. - PMC - PubMed

Publication types

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