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Comment
. 2016 Apr 12;23(4):571-3.
doi: 10.1016/j.cmet.2016.03.012.

VEGF-B Improves Metabolic Health through Vascular Pruning of Fat

Shahin Rafii  1 , Peter Carmeliet  2
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VEGF-B Improves Metabolic Health through Vascular Pruning of Fat

Shahin Rafii et al. Cell Metab. .
Free article

Abstract

Unraveling the mechanism VEGF-receptors modulating metabolism has therapeutic implications. In this issue, Robciuc et al. (2016) demonstrate that VEGF-B, by displacing VEGF-A from VEGFR1 and activating VEGFR2, increases adipose tissue vascularity, improves insulin sensitivity, diminishes obesity, and alleviates metabolic syndrome.

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