The Plot Thickens: Diet Microbe Interactions May Modulate Thrombosis Risk
- PMID: 27076072
- DOI: 10.1016/j.cmet.2016.03.017
The Plot Thickens: Diet Microbe Interactions May Modulate Thrombosis Risk
Abstract
Thrombosis plays an important role in cardiovascular disease (CVD). Platelet activation is an essential step in the genesis and propagation of atherothrombotic complications. In a recent publication, Zhu and colleagues report that gut microbe-derived TMAO enhances platelet responsiveness and thrombosis, providing a novel mechanistic connection between microbes and CVD (Zhu et al., 2016).
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.Cell. 2016 Mar 24;165(1):111-124. doi: 10.1016/j.cell.2016.02.011. Epub 2016 Mar 10. Cell. 2016. PMID: 26972052 Free PMC article.
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