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Review
. 2016 Apr 10;7(7):153-64.
doi: 10.4239/wjd.v7.i7.153.

Diabetic foot disease: From the evaluation of the "foot at risk" to the novel diabetic ulcer treatment modalities

Noha Amin  1 , John Doupis  1
Affiliations
Review

Diabetic foot disease: From the evaluation of the "foot at risk" to the novel diabetic ulcer treatment modalities

Noha Amin et al. World J Diabetes. .

Abstract

The burden of diabetic foot disease (DFD) is expected to increase in the future. The incidence of DFD is still rising due to the high prevalence of DFD predisposing factors. DFD is multifactorial in nature; however most of the diabetic foot amputations are preceded by foot ulceration. Diabetic peripheral neuropathy (DPN) is a major risk factor for foot ulceration. DPN leads to loss of protective sensation resulting in continuous unconscious traumas. Patient education and detection of high risk foot are essential for the prevention of foot ulceration and amputation. Proper assessment of the diabetic foot ulceration and appropriate management ensure better prognosis. Management is based on revascularization procedures, wound debridement, treatment of infection and ulcer offloading. Management and type of dressing applied are tailored according to the type of wound and the foot condition. The scope of this review paper is to describe the diabetic foot syndrome starting from the evaluation of the foot at risk for ulceration, up to the new treatment modalities.

Keywords: Diabetes; Diabetic complications; Diabetic foot; Diabetic macroanggiopathy; Diabetic neuropathy; Diabetic ulcer.

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Figures

Figure 1
Figure 1
A neuropathic ulcer in a patient with severe diabetic peripheral neuropathy.
Figure 2
Figure 2
Gangrene in a patient with type 2 diabetes and severe peripheral arterial disease.
See this image and copyright information in PMC

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