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Review
. 2016 Mar 1:7:48.
doi: 10.4103/2008-7802.177893. eCollection 2016.

Meta-analysis of the Prevalence of Helicobacter Pylori Infection among Children and Adults of Iran

Mahmood Moosazadeh  1 , Kamran B Lankarani  2 , Mahdi Afshari  3
Affiliations
Review

Meta-analysis of the Prevalence of Helicobacter Pylori Infection among Children and Adults of Iran

Mahmood Moosazadeh et al. Int J Prev Med. .

Abstract

Helicobacter pylori infection is a common health problem related to many gastrointestinal disorders. This study aims to estimate the total and age specific prevalence of Helicobacter Pylori infection in Iran. We systematically reviewed all national and international databases and finally identified 21 studies were eligible for meta-analysis. Each of them were assigned a quality score using STROBE checklist. Due to significant heterogeneity of the results, random effects model was used to estimate the pooled prevalence and 95% confidence interval of Helicobacter Pylori infection. All statistical analyses were performed using STATA. V11 software. The pooled prevalence (95% confidence interval) of Helicobacter Pylori infection among all population, children and adults were estimated as 54% (53%- 55%), 42% (41%- 44%) and 62% (61%- 64%) respectively. Helicobacter Pylori, has infected more than half of Iranian people during the last decade. Preventive strategies as well as taking into account this infection during clinical visits should be emphasized to reduce its transmission and prevalence within the community.

Keywords: Helicobacter; Iran; meta-analysis; prevalence.

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Figures

Figure 1
Figure 1
Literature search and review flowchart for selection of primary studies
Figure 2
Figure 2
Forest plot for prevalence of Helicobacter pylori infection in Iran
Figure 3
Figure 3
Forest plots indicating the prevalence rates of Helicobacter pylori infection among children
Figure 4
Figure 4
Forest plots indicating the prevalence rates of Helicobacter pylori infection among adults
See this image and copyright information in PMC

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