Review
Drugs for Pulmonary Arterial Hypertension: Comparative Efficacy, Safety, and Cost-Effectiveness [Internet]
Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2015 Mar.
Affiliations
- PMID: 27077175
- Bookshelf ID: NBK355844
Item in Clipboard
Review
Drugs for Pulmonary Arterial Hypertension: Comparative Efficacy, Safety, and Cost-Effectiveness [Internet]
Excerpt
The objective of this therapeutic review is to conduct a systematic review to assess the comparative efficacy and safety and to determine the cost-effectiveness of drug therapies for the treatment of pulmonary arterial hypertension (PAH) in adults.
Copyright © 2015 CADTH.
Sections
- ABBREVIATIONS AND GLOSSARY
- EXECUTIVE SUMMARY
- 1. CONTEXT AND POLICY ISSUES
- 2. POLICY QUESTIONS
- 3. RESEARCH QUESTIONS
- 4. METHODS
- 5. RESULTS
- 6. DISCUSSION
- 7. CONCLUSIONS AND IMPLICATIONS FOR DECISION-OR POLICY-MAKING
- REFERENCES
- APPENDIX 1. PATIENT INPUT INFORMATION
- APPENDIX 2. VALIDITY OF OUTCOMES
- APPENDIX 3. LITERATURE SEARCH STRATEGY
- APPENDIX 4. SELECTION OF INCLUDED STUDIES
- APPENDIX 5. INCLUDED STUDY LIST
- APPENDIX 6. EXCLUDED STUDY LIST
- APPENDIX 7. CHARACTERISTICS OF INCLUDED STUDIES
- APPENDIX 8. CRITICAL APPRAISAL OF INCLUDED STUDIES
- APPENDIX 9. DETAILED DATA OF MONOTHERAPY AND ADD-ON THERAPY TRIALS
- APPENDIX 10. PAIRWISE META-ANALYSES
- APPENDIX 11. COMPARISONS OF PAIRWISE META-ANALYSES AND NETWORK META-ANALYSES
- APPENDIX 12. COMPLETE RESULTS OF NETWORK META-ANALYSIS
- APPENDIX 13. QUALITY OF LIFE
- APPENDIX 14. COMBINATION THERAPY IN PULMONARY ARTERIAL HYPERTENSION — STUDIES NOT INCLUDED IN THERAPEUTIC REVIEW
- APPENDIX 15. REVIEW OF PREVIOUS PHARMACOECONOMIC ANALYSES
- APPENDIX 16. SCHEMATIC OF MARKOV MODEL
- APPENDIX 17. CLINICAL PARAMETERS FOR THE ECONOMIC MODEL
- APPENDIX 18. RESOURCE USE ESTIMATES FOR THE ECONOMIC MODEL
- APPENDIX 19. BREAKDOWN OF COSTS BY COST CATEGORY
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