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Comment
. 2016 Apr 13;19(4):432-3.
doi: 10.1016/j.chom.2016.04.001.

Adding Insult to Injury: Exacerbating TB Risk with Smoking

Michael S Glickman  1 , Neil Schluger  2
Affiliations
Comment

Adding Insult to Injury: Exacerbating TB Risk with Smoking

Michael S Glickman et al. Cell Host Microbe. .

Abstract

Inhaled environmental pollutants, most prominently from cigarettes, confer an increased risk of tuberculosis. A recent study published in Cell by Berg et al., (2016) using the zebrafish model of Mycobacterium marinum infection provides new insights into the role of macrophage lysosomal engorgement in compromising host defense against mycobacteria.

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References

    1. Berg RD, Levitte S, O’Sullivan MP, O’Leary SM, Cambier CJ, Cameron J, Takaki KK, Moens CB, Tobin DM, Keane J, Ramakrishnan L. Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration. Cell. 2016;165:139–152. - PMC - PubMed
    1. Eriksen M, Mackay J, Schluger N, Gomeshtapheh F, D J. The Tobacco Atlas. Atlanta: 2015.
    1. Lai TC, Chiang CY, Wu CF, Yang SL, Liu DP, Chan CC, Lin HH. Ambient air pollution and risk of tuberculosis: a cohort study. Occup Environ Med. 2016;73:56–61. doi: 10.1136/oemed-2015-102995. - DOI - PubMed
    1. Leung CC, Yew WW, Chan CK, Chang KC, Law WS, Lee SN, Tai LB, Leung ECC, Au RKF, Huang SS, Tam CM. Smoking adversely affects treatment response, outcome and relapse in tuberculosis. Eur Respir J. 2015;45:738–45. doi: 10.1183/09031936.00114214. - DOI - PubMed
    1. Lin H-H, Suk CW, Lo H-L, Huang RY, Enarson DA, Chiang C-Y. Indoor air pollution from solid fuel and tuberculosis: a systematic review and meta-analysis. Int J Tuberc Lung Dis. 2014;18:613–21. doi: 10.5588/ijtld.13.0765. - DOI - PubMed

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